Pluvia Consumer Health

Pharmacokinetics:

Absorption: Orally absorbed, but undergoes extensive first-pass metabolism in the liver, resulting in low bioavailability (around 3-5%).
Distribution: Binds extensively to plasma proteins.
Metabolism: Extensively metabolized in the liver to various metabolites, mostly inactive.
Elimination: Primarily eliminated through the feces, with a small amount excreted in the urine.
Half-life: Approximately 6-8 hours.

Pharmacological Actions:
Antitussive: Suppresses cough reflex by acting on the cough center in the medulla oblongata.
Bronchodilatory: Relaxes bronchial smooth muscle, but the effect is weak and of limited clinical significance.
Vasodilatory: Dilates blood vessels, but the effect is weak and transient.
Other: Weak analgesic, antihistaminic, and anti-inflammatory effects.